In spite of its promising role in the treatment of several disorders, there are some limitations to the use of these cells in scientific research and clinical therapy.

 

In the context of orthopedic pathology, many studies and clinical trials have been conducted in order to regenerate the different tissues of the locomotor system (bone, cartilage, intervertebral disc, tendons, ligaments and muscles).

 

The potential of stem cells to differentiate into bone was found in several studies when a microenvironment with growth factors and other proteins was present. Pseudarthrosis and osteogenesis imperfecta are the two types of orthopedic disorders with promising results when stem cells are used as well as the regeneration of articular cartilage, fibrocartilage, intervertebral discs, tendons and ligaments.

 

The treatment of muscle disorders has been studied outside the spectrum of orthopedic pathologies.

 

This bibliographic review aims to gather information from publications concerning the clinical use of stem cells in Orthopedics.

 

 

Keywords: Stem cells, Orthopedics, Bone, Cartilage